diff --git a/drivers/accel/amdxdna/amdxdna_mailbox.c b/drivers/accel/amdxdna/amdxdna_mailbox.c
index da1ac89bb78f..6634a4d5717f 100644
--- a/drivers/accel/amdxdna/amdxdna_mailbox.c
+++ b/drivers/accel/amdxdna/amdxdna_mailbox.c
@@ -513,6 +513,7 @@ xdna_mailbox_create_channel(struct mailbox *mb,
 	}
 
 	mb_chann->bad_state = false;
+	mailbox_reg_write(mb_chann, mb_chann->iohub_int_addr, 0);
 
 	MB_DBG(mb_chann, "Mailbox channel created (irq: %d)", mb_chann->msix_irq);
 	return mb_chann;